Severity of Obstructive Sleep Apnoea Is Associated With Elevated Plasma Fibrinogen in Otherwise Healthy Patients

Obstructive sleep apnoea is associated with cardiovascular diseases. Cardiovascular pathophysiology in OSA patients is associated with coagulation and systemic inflammation. This is caused by fibrinogen which is a major coagulation protein that leads to inflammation and major cardiovascular diseases. Fibrinogen levels are directly related to apnoea hypopnoea index (AHI), arousal index and are inversely related to the lowest oxygen saturation during sleep.

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Somnowell Inventor - Visiting Professor Simon Ash FDS MSc MOrth BDS

Prof. Ash is the inventor of the highly successful SOMNOWELL Chrome device for snoring and sleep apnoea.

The Somnowell Chrome is made to exacting standards in the Somnowell laboratory under the supervision of Visiting Professor Simon Ash. Prof. Ash and his master technicians create each Somnowell Chrome device using their wealth of experience and expertise.

Prof. Ash works at the forefront of his profession. He is a Consultant and Specialist Orthodontist with over 30 years clinical experience, with a special interest in sleep related breathing disorders, TMJD, and bruxism. He currently works in Harley Street London and two private hospitals in London as part of a multi-disciplinary team managing snoring and sleep apnoea, and is Visiting Professor of Orthodontics at the BPP University.