Severity of Decreased Breathing Episodes, Rather Than Their Frequency, Improves Prediction of Cardiovascular Events in OSA
Research shows that obstructive sleep apnoea is associated with the increased risk for cardiovascular disease. For a long time, Apnoea-Hypopnoea Index (AHI) has been the single most useful predictor for cardiovascular disease. AHI is described as the number of time breathing is paused or is severely slowed per hour of sleep.
Researchers led by Tetyana Kendzerska from the University of Toronto led a cohort study of 10,140 patients who were diagnosed for sleep apnoea through polysomnography between 1994 and 2000. From the findings of the study, when other OSA-related factors were added to the model, AHI was no longer a significant predictor of the composite outcome.
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Somnowell Inventor - Visiting Professor Simon Ash FDS MSc MOrth BDS

Prof. Ash is the inventor of the highly successful SOMNOWELL Chrome device for snoring and sleep apnoea.
The Somnowell Chrome is made to exacting standards in the Somnowell laboratory under the supervision of Visiting Professor Simon Ash. Prof. Ash and his master technicians create each Somnowell Chrome device using their wealth of experience and expertise.
Prof. Ash works at the forefront of his profession. He is a Consultant and Specialist Orthodontist with over 30 years clinical experience, with a special interest in sleep related breathing disorders, TMJD, and bruxism. He currently works in Harley Street London and two private hospitals in London as part of a multi-disciplinary team managing snoring and sleep apnoea, and is Visiting Professor of Orthodontics at the BPP University.
The Somnowell mandibular advancement appliance is also recommended by:
- Sleep Centres
- ENT Surgeons, Sleep Physicians, Respiratory, Physicians
- Orthodontists, Dentists
- General Medical Practitioners
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