Obstructive Sleep Apnoea Modulates Airway Inflammation and Remodelling in Severe Asthma
The role of obstructive sleep apnoea (OSA)-related systemic and airway neutrophilic inflammation in asthma bronchial inflammation or remodelling has been hardly investigated. The study sought to compare the hallmarks of inflammation in induced sputum and features of airway remodelling in bronchial biopsies from adult patients with severe asthma with and without OSA. Researchers found that mild OSA in patients with severe asthma is associated with increased proportion of neutrophils in sputum and changes in airway remodelling.
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Somnowell Inventor - Visiting Professor Simon Ash FDS MSc MOrth BDS
Prof. Ash is the inventor of the highly successful SOMNOWELL Chrome device for snoring and sleep apnoea.
The Somnowell Chrome is made to exacting standards in the Somnowell laboratory under the supervision of Visiting Professor Simon Ash. Prof. Ash and his master technicians create each Somnowell Chrome device using their wealth of experience and expertise.
Prof. Ash works at the forefront of his profession. He is a Consultant and Specialist Orthodontist with over 30 years clinical experience, with a special interest in sleep related breathing disorders, TMJD, and bruxism. He currently works in Harley Street London and two private hospitals in London as part of a multi-disciplinary team managing snoring and sleep apnoea, and is Visiting Professor of Orthodontics at the BPP University.
The Somnowell mandibular advancement appliance is also recommended by:
- Sleep Centres
- ENT Surgeons, Sleep Physicians, Respiratory, Physicians
- Orthodontists, Dentists
- General Medical Practitioners