Association of Glucose Transporter 4 Genetic Polymorphisms with OSA Syndrome in Han Chinese General Population: A cross-section

Obstructive sleep apnoea can lead to stroke, heart disease and metabolic syndrome. A recent study assessed whether GLUT4 gene polymorphisms are associated with OSAS. Patients hospitalized at People's Hospital of Xinjiang were selected from January to December 2010. The authors performed GLUT4 genome sequencing and found 4 mutated sites. This study demonstrates that GLUT4 gene SNPrs5417 is associated with OSAS in a hypertensive population. Carriers of AA + AC have less prevalence of obstructive sleep apnoea syndrome than that of CC carriers.

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Somnowell Inventor - Visiting Professor Simon Ash FDS MSc MOrth BDS

Prof. Ash is the inventor of the highly successful SOMNOWELL Chrome device for snoring and sleep apnoea.

The Somnowell Chrome is made to exacting standards in the Somnowell laboratory under the supervision of Visiting Professor Simon Ash. Prof. Ash and his master technicians create each Somnowell Chrome device using their wealth of experience and expertise.

Prof. Ash works at the forefront of his profession. He is a Consultant and Specialist Orthodontist with over 30 years clinical experience, with a special interest in sleep related breathing disorders, TMJD, and bruxism. He currently works in Harley Street London and two private hospitals in London as part of a multi-disciplinary team managing snoring and sleep apnoea, and is Visiting Professor of Orthodontics at the BPP University.